The massive test effort , dubbed ‘Operation Warp Speed’ will compress years of trails into several months to verify vaccine’s that could available by years end….
The trails will start with the two most advanced candidates, made by Moderna Inc and Britain’s Oxford University and AstraZeneca Plc,…
Several other companies…Johnson & Johnson, Sanofi and Merck & Co have vaccines that could join the effort and could increase the sample population by up to 50,000 additional volunteers…There are as many as 14 different vaccine’s being worked on…
The vaccine companies have said their entries could be available possibly by the fall….
Dr. Fauci thinks the earliest a vaccine could to go out to the public could be December or January….One should remember that President Trump has pushed other treatment drugs out to the public much earlier then the ‘expert’s ‘ though should be done….
The United States plans a massive testing effort involving more than 100,000 volunteers and a half dozen or so of the most promising vaccine candidates in an effort to deliver a safe and effective one by the end of 2020, scientists leading the program told Reuters.
The project will compress what is typically 10 years of vaccine development and testing into a matter of months, testimony to the urgency to halt a pandemic that has infected more than 5 million people, killed over 335,000 and battered economies worldwide.
To get there, leading vaccine makers have agreed to share data and lend the use of their clinical trial networks to competitors should their own candidate fail, the scientists said.
Candidates that demonstrate safety in small early studies will be tested in huge trials of 20,000 to 30,000 subjects for each vaccine, slated to start in July.
Between 100,000 and 150,000 people may be enrolled in the studies, said Dr. Larry Corey, a vaccine expert at Fred Hutchinson Cancer Center in Seattle, who is helping design the trials. “If you don’t see a safety problem, you just keep going,” Dr. Francis Collins, director of the National Institutes of Health (NIH), told Reuters. The vaccine effort is part of a public-private partnership called Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) announced last month.
The effort fits into the research and development arm of “Operation Warp Speed,” the White House program announced last week to accelerate coronavirus vaccine development. Vaccines, which are intended for use in healthy people, are typically tested in successive steps, starting with trials in animals.
Human testing begins with a small safety trial in healthy volunteers, followed by a larger study to find the right dose and get an early read on efficacy. The final stage consists of large-scale testing in thousands of people. Only then would a vaccine developer commit to manufacturing millions of doses. In the era of coronavirus, many of those steps will overlap, particularly the mid-stage and late-stage trials, Collins and Corey said…..
Image..XINHUA/ALAMY STOCK PHOTO
Most scientific works that I have perused find all this talk wildly optimistic.
They seem to feel that almost all this talk is being generated by the White House and it’s minions as well as big pharmaceutical companies that are using such to drive up their stock values(there already exists anecdotal evidence of this with the Moderna situation).
Most of what I’ve read believes the earliest a safe effective vaccine “ might” be available would be about a year from now .With widespread distribution not available till the latter part of 2021.
I’m sure we all hope for the earliest possible dates;however, some of these dates being thrown around do not seem realistic to me.
Actually Fauci has joined the end of the year chorus….
I still think Trump will push an ok for one or two of the vaccine ahed of November 3rd…
He was wrong about the malaria drug and I don’t think he actually took it…
But he IS the President’s and he will have no problems with putting his political fortune ahead of people’s health as he has in trying to rush the reopening’s
I’m not sure how this will work so please explain.
So you are saying a pharmaceutical company will invest billions of dollars in producing a vaccine that scientifically won’t work so Trump can “push” it?
The comparison to quinine isn’t the same.Thats a heap drug that has been around for years.
A new vaccine to mass distribute would cost hundreds of millions of dollars.
Another “weird” illogical post.
Jack?
Trump has committed OVER a Billion Dollars to buy doses BEFORE the trails are done…
Really?
What don’t u get?
Where is the vaccine then?
If the vaccine is going to be purchased “before the trials are done”why isn’t it being produced as we speak?
What are they waiting on?
There are Billions to be made!
You’re pathetic in your ignorance.
He, he, he…..
It OUR tax dollars the President is spending…
He’s the one u ought be annoyed at…
What you posted was a total fabrication.
The government has appropriated billions to assist in the development of an effective vaccine, a worthy expenditure in my view.
Your claim That Trump has committed that money to “buy doses” before any trials has no basis in fact.
You really need to give it a rest.Ever since this pandemic struck you have engaged in overwrought statements downplaying it’s legality and making totally unsubstantiated statements that are easily refuted.
Actually it appears to me this whole thing has sort have thrown you for a loop and somehow you think that by pretending that things are true which in many cases demonstrably aren’t and making “predictions “ (there would be a vaccine by midsummer) that strain credulity will somehow make things better.
Really, give it a rest.You are simply embarrassing yourself.
Lethality not legality.
Jack?
Ya need to stop fighting this…
Trump IS gonna do what HE wants until he loses his day job…
…
Warp Speed has so far identified 14 COVID-19 vaccine possibilities. It will select the eight most promising and provide coordinated government support for their development and testing in early stage small clinical trials. Large-scale randomized trials will proceed in three to five of them.
As of Thursday, four vaccine coronavirus candidates had received major funding by the U.S. government:
BARDA’s up to $1.2 billion for early access to 300 million doses of British drugmaker AstraZeneca’s experimental COVID-19 vaccine
Johnson and Johnson through its Janssen Pharmaceutical subsidiary has gotten at least $456 million in coronavirus vaccine funding from the Office of the Assistant Secretary for Preparedness and Response
Moderna received more than $483 million from BARDA
Sanofi has received at least $30 million from BARDA
Whether these four that have been funded represent the semi-finalists is not known….
More…
The only thing I’m “fighting” is your “misstatements, “notice I am being charitable today and not calling you what you really are .
These articles have nothing to do with what you wrote.
I presume everyone is in favor of continuing efforts to develop a reliable vaccine.
That’s not at issue.
My posts were directing attention to your clear misstatement of facts.
in fact i state the ‘facts’
then u jump some place else….
it’s ALL Good!
Furthermore…
Operation Warp Speed appears to have access to substantial resources. Congress has directed almost $10 billion through supplemental funding, including the CARES Act. In addition, over $6.5billion was designated for countermeasure development through BARDA and $3 billion for NIH research…
More….
I posted here that first test’s are supposed to involve OVER 100,000 to 150,000 subjects…
And the testing has already started…
And they are having issues because the infection rate is declining…
This is about this weeks tests for Oxford…
…
The Oxford University team in charge of developing a coronavirus vaccine said a decline in the infection rate will make it increasingly difficult to prove whether it’s been successful, the Telegraph reported.
“It’s a race against the virus disappearing, and against time,” Professor Adrian Hill, director of the university’s Jenner Institute, told the newspaper. “We said earlier in the year that there was an 80% chance of developing an effective vaccine by September. But at the moment, there’s a 50% chance that we get no result at all.”
Hill said he expects fewer than 50 of the 10,000 people who have volunteered to test the vaccine trial in coming week to catch the virus. If fewer than 20 test positive, the results may be useless, the newspaper cited him as saying.
More…
(Please notice the mention of September and YES…This IS a high stakes rush…U betcha!)
And of course none of this has anything to do with your statement which is the subject of what started this,
“Trump has committed over a billion dollars to BUY DOSES( emphasis added) before any trials are done.”
That is not true .The money was “committed” for development and trials.No “doses” have been bought because , as yet, there is nothing to “buy.”
All you’ve done is posted articles as to the testing of these vaccines that may or may not prove viable.That was where the money was committed .
You are one of the most obtuse people I’ve ever known.
He, he, he…..
The US Govt. Has a Purchase order in Jack….
He, he, he….
You ARE wiggling and dancing HARD on this…
The US government ‘pays’ for stuff ALL the time before it actually gets it….
So does most businesses…
They ARE testing the vaccine…
ARE…
They have them…
Not ONE company …
But a whole lot…
Yes…I HAVE said here that some may not make it…
But my contention is that any one that shows a breath of success is gonna have Trump press the go button which will have the company manufacture the drug…
The money to do so is there …
It just takes a bottom press…
And THAT isn’t development Jack…
300 million doses have been reserved….AND PAID FOR ALREADY…
I’m really having a good time on this…
Show us please the uh”purchase order.”
I’m sure CNN NBC and yes Fox would be interested.
So we are all straight on this…
You’re claiming that there the United States government has contracted to purchase an item that as yet doesn’t exist…
An effective vaccine for coronavirus.
Oh ,have a ball with your delusions.
Time for me to take a long break!
Voila!
I kinda knew that was coming
Take care….
I’ll catch ya in a few